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1

Apoptosis Induced by Molecular Targeting Therapy in Hematological Malignancies

Adachi, Souichi, Leoni, Lorenzo M., Carson, Dennis A., Nakahata, Tatsutoshi

Journal:

Acta Haematologica

Year:

2004

Language:

english

File:

PDF, 283 KB

english, 2004

2

Effect of cocaine and morphine on neutral endopeptidase activity of human peripheral blood mononuclear cells cultured with lectins

Lorenzo M. Leoni, Dr Gabriele A. Losa

Journal:

Cell Biochemistry and Function

Year:

1993

Language:

english

File:

PDF, 761 KB

english, 1993

3

Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles

Dominique P. Pioletti, Lorenzo Leoni, Davide Genini, Hiroshi Takei, Pinyi Du, Jacques Corbeil

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

2002

Language:

english

File:

PDF, 951 KB

english, 2002

4

R-etodolac (SDX-101) and the related indole–pyran analogues SDX-308 and SDX-309 potentiate the antileukemic activity of standard cytotoxic agents in primary chronic lymphocytic leukaemia cells

Elin Lindhagen, Sara Nissle, Lorenzo Leoni, Gary Elliott, Qi Chao, Rolf Larsson, Anna Åleskog

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 398 KB

english, 2007

5

Pharmacological profiling of novel non-COX-inhibiting indole-pyran analogues of etodolac reveals high solid tumour activity of SDX-308 in vitro

Elin Lindhagen, Linda Rickardson, Gary Elliott, Lorenzo Leoni, Peter Nygren, Rolf Larsson, Anna Åleskog

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

6

Intravesical Toll-like receptor 7 agonist R-837: Optimization of its formulation in an orthotopic mouse model of bladder cancer

Tomoko Hayashi, Brian Crain, Maripat Corr, Michael Chan, Howard B Cottam, Roberto Maj, Alcide Barberis, Lorenzo Leoni, Dennis A Carson

Journal:

International Journal of Urology

Year:

2010

Language:

english

File:

PDF, 542 KB

english, 2010

7

Pharmacokinetics and toxicity of intravesical TMX-101: a preclinical study in pigs

Harm C. Arentsen, Christina A. Hulsbergen-Van de Kaa, Cornelius F.J. Jansen, Roberto Maj, Lorenzo M. Leoni, Egbert Oosterwijk, J. Alfred Witjes

Journal:

BJU International

Year:

2011

Language:

english

File:

PDF, 447 KB

english, 2011

8

10.1038/82248

Albani, Salvatore, Prakken, Berent, Wauben, Marca, Genini, Davide, Samodal, Rodrigo, Barnett, Joellen, Mendivil, Alberto, Leoni, Lorenzo

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 111 KB

english, 2000

9

10.1038/82236

Albani, Salvatore, Prakken, Berent, Wauben, Marca, Genini, Davide, Samodal, Rodrigo, Barnett, Joellen, Mendivil, Alberto, Leoni, Lorenzo

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 946 KB

english, 2000

10

10.1038/82242

Albani, Salvatore, Prakken, Berent, Wauben, Marca, Genini, Davide, Samodal, Rodrigo, Barnett, Joellen, Mendivil, Alberto, Leoni, Lorenzo

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 309 KB

english, 2000

11

10.1038/82231

Albani, Salvatore, Prakken, Berent, Wauben, Marca, Genini, Davide, Samodal, Rodrigo, Barnett, Joellen, Mendivil, Alberto, Leoni, Lorenzo

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 825 KB

english, 2000

12

10.1038/82252

Albani, Salvatore, Prakken, Berent, Wauben, Marca, Genini, Davide, Samodal, Rodrigo, Barnett, Joellen, Mendivil, Alberto, Leoni, Lorenzo

Journal:

Nature Biotechnology

Year:

2000

Language:

english

File:

PDF, 69 KB

english, 2000

13

10.1038/82246

Albani, Salvatore, Prakken, Berent, Wauben, Marca, Genini, Davide, Samodal, Rodrigo, Barnett, Joellen, Mendivil, Alberto, Leoni, Lorenzo

Journal:

Nature Medicine

Year:

2000

File:

PDF, 106 KB

2000

14

Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion

Hustinx, Steven R, Leoni, Lorenzo M, Yeo, Charles J, Brown, Priscilla N, Goggins, Michael, Kern, Scott E, Hruban, Ralph H, Maitra, Anirban

Journal:

Modern Pathology

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

15

Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas

Rhee, Chae-Seo, Sen, Malini, Lu, Desheng, Wu, Christina, Leoni, Lorenzo, Rubin, Jeffrey, Corr, Maripat, Carson, Dennis A

Journal:

Year:

2002

Language:

english

File:

PDF, 251 KB

english, 2002

16

Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARγ

Michael Hedvat, Anjali Jain, Dennis A Carson, Lorenzo M Leoni, Ganghua Huang, Stuart Holden, Desheng Lu, Maripat Corr, William Fox, David B Agus

Journal:

Year:

2004

Language:

english

File:

PDF, 404 KB

english, 2004

17

Tonic modulation of neurotransmitter release in the guinea-pig myenteric plexus: effect of μ and κ opioid receptor blockade and of chronic sympathetic denervation

Marco Cosentino, Franca Marino, Fabrizio De Ponti, Cristina Giaroni, Lorenzo Somaini, Olivia Leoni, Sergio Lecchini, Gianmario Frigo

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 489 KB

english, 1995

18

Effects of angiotensin II and insulin on ERK1/2 activation in fibroblasts from hypertensive patients

Michelangelo Sartori, Giulio Ceolotto, Italia Papparella, Elisabetta Baritono, Laura Ciccariello, Lorenzo Calò, Matteo Leoni, Andrea Semplicini

Journal:

American Journal of Hypertension

Year:

2004

Language:

english

File:

PDF, 233 KB

english, 2004

19

Structural characterization of the Costa Rica décollement: Evidence for seismically-induced fluid pulsing

Paola Vannucchi, Lorenzo Leoni

Journal:

Earth and Planetary Science Letters

Year:

2007

Language:

english

File:

PDF, 3.37 MB

english, 2007

20

R-Etodolac decreases β-catenin levels along with survival and proliferation of hepatoma cells

Jaideep Behari, Gang Zeng, Wade Otruba, Michael D. Thompson, Peggy Muller, Amanda Micsenyi, Sandeep S. Sekhon, Lorenzo Leoni, Satdarshan P.S. Monga

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 2.70 MB

english, 2007

21

Granulocytopenia after combined therapy with interferon and angiotensin-converting enzyme inhibitors: Evidence for a synergistic hematologic toxicity

Milyia Casato, Leopoldo P. Pucillo, Marco Leoni, Luca di Lullo, Armando Gabrielli, Domenico Sansonno, Franco Dammacco, Giovanni Danieli, Lorenzo Bonomo

Journal:

The American Journal of Medicine

Year:

1995

Language:

english

File:

PDF, 675 KB

english, 1995

22

Acetylcholine detection by a modified HPLC-ED method improves the assessment of cholinergic function in the myenteric plexus of the guinea-pig colon

Cristina Giaroni, Lorenzo Somaini, Franca Marino, Marco Cosentino, Olivia Leoni, Fabrizio De Ponti, Sergio Lecchini, Gianmario Frigo

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

23

The Evolving Role of Bendamustine in Lymphoid Malignancy: Understanding the Drug and Its Mechanism of Action—Introduction

Lorenzo M. Leoni

Journal:

Seminars in Hematology

Year:

2011

Language:

english

File:

PDF, 197 KB

english, 2011

24

Mechanism of Action: The Unique Pattern of Bendamustine-Induced Cytotoxicity

Lorenzo M. Leoni, John A. Hartley

Journal:

Seminars in Hematology

Year:

2011

Language:

english

File:

PDF, 438 KB

english, 2011

25

Conclusion and Future Directions

Lorenzo M. Leoni

Journal:

Seminars in Hematology

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

26

Bendamustine: Rescue of an Effective Antineoplastic Agent From the Mid-Twentieth Century

Lorenzo M. Leoni

Journal:

Seminars in Hematology

Year:

2011

Language:

english

File:

PDF, 534 KB

english, 2011

27

O-29 The methylthioadenosine phosphorylase (MTAP) gene is homozygously co-deleted with CDKN2A in most pleural mesotheliomas. Detection by fluorescent in situ hybridization (FISH) and by immunohistochemistry (IHC) using a novel MTAP monoclonal antibody

Illeil, Peter B., Leoni, Lorenzo, Huang, Weidong, Astrow, Stephanie, Cheeks, Alan, Rusch, Valerie, Ladanvi, Marc

Journal:

Year:

2003

Language:

english

File:

PDF, 173 KB

english, 2003

28

Modulation of Ceramide-Activated Protein Phosphatase 2A Activity by Low Molecular Weight Aromatic Compounds

Lorenzo M. Leoni, Hsien C. Shih, Lynn Deng, Chuck Tuey, Gernot Walter, Dennis A. Carson, Howard B. Cottam

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 470 KB

english, 1998

29

Hairy-cell leukaemia as a model for drug development

Dennis A Carson, Lorenzo M Leoni

Journal:

Best Practice & Research Clinical Haematology

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

30

Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis

Daniel Rachmilewitz, Fanny Karmeli, Kenji Takabayashi, Tomoko Hayashi, Leonor Leider-Trejo, Jongdae Lee, Lorenzo M. Leoni, Eyal Raz

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 3.02 MB

english, 2002

31

Substituted Isoquinolines and Quinazolines as Potential Antiinflammatory Agents. Synthesis and Biological Evaluation of Inhibitors of Tumor Necrosis Factor α

Chao, Qi, Deng, Lynn, Shih, Hsiencheng, Leoni, Lorenzo M., Genini, Davide, Carson, Dennis A., Cottam, Howard B.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 192 KB

english, 1999

32

978 PHARMACOKINETICS AND TOXICITY OF INTRAVESICAL TMX-101: A PRECLINICAL STUDY IN PIGS

Arentsen, Harm, Hulsbergen-van de Kaa, Christina, Jansen, Kees, Maj, Roberto, Leoni, Lorenzo, Oosterwijk, Egbert, Witjes, Fred

Journal:

The Journal of Urology

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

33

A New Reporter Cell Line to Monitor HIV Infection and Drug Susceptibility in vitro

Alain Gervaix, Daniel West, Lorenzo M. Leoni, Douglas D. Richman, Flossie Wong-Staal and Jacques Corbeil

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.49 MB

english, 1997

34

Induction of an Apoptotic Program in Cell-Free Extracts by 2-Chloro-2′-deoxyadenosine 5′-Triphosphate and Cytochrome c

Lorenzo M. Leoni, Qi Chao, Howard B. Cottam, Davide Genini, Michael Rosenbach, Carlos J. Carrera, Imawati Budihardjo, Xiaodong Wang and Dennis A. Carson

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.44 MB

english, 1998

35

Hyperfractionated radiotherapy and concomitant cisplatin in Stage III non-small cell lung cancer: a Phase II study by the AIRO-Lombardia Cooperative Group

Palazzi, Mauro, Morrica, Brunello, Montanaro, Paolo, Cerizza, Lorenzo, Leoni, Mario

Journal:

Year:

1996

Language:

english

File:

PDF, 398 KB

english, 1996

36

A pediatric case report of acute intermittent porphyria: Learning the lesson

Rosafio, Cristiano, Bergonzini, Patrizia, Marchini, Stefano, Leoni, Stefania, Fusco, Carlo, Colli, Serena, Pietrangelo, Antonello, Paolucci, Paolo, Ventura, Paolo, Lughetti, Lorenzo

Journal:

Digestive and Liver Disease

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

37

Two Point Mutations within the Adducin Genes are Involved in Blood Pressure Variation

Giuseppe Bianchi, Grazia Tripodi, Giorgio Casari, Sergio Salardi, Barry R. Barber, Rodolfo Garcia, Patricia Leoni, Lucia Torielli, Daniele Cusi, Mara Ferrandi, Lorenzo A. Pinna, Francisco E. Baralle a

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.03 MB

english, 1994

38

[IEEE 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Osaka (2013.7.3-2013.7.7)] 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Rollable and implantable intraocular pressure sensor for the continuous adaptive management of glaucoma

Piffaretti, Filippo, Barrettino, Diego, Orsatti, Paolo, Leoni, Lorenzo, Stegmaier, Peter

Year:

2013

Language:

english

File:

PDF, 2.14 MB

english, 2013

39

Deformation pattern in the underthrust carbonate-rich sequence of the Sibillini Thrust (central Italy): insights for shear zone evolution in modern subduction complexes

Leoni, Lorenzo, Vannucchi, Paola, Principi, Gianfranco, Catani, Filippo

Journal:

Geodinamica Acta

Year:

2007

Language:

english

File:

PDF, 5.48 MB

english, 2007

40

Chronic fatigue is the most important factor limiting health-related quality of life of chronic myeloid leukemia patients treated with imatinib

Efficace, F, Baccarani, M, Breccia, M, Cottone, F, Alimena, G, Deliliers, G L, Baratè, C, Specchia, G, Di Lorenzo, R, Luciano, L, Turri, D, Martino, B, Stagno, F, Dabusti, M, Bergamaschi, M, Leoni, P,

Journal:

Year:

2013

Language:

english

File:

PDF, 1.48 MB

english, 2013

41

Polyclonal Proliferation and Apoptosis of CCR5 + T Lymphocytes during Primary Human Immunodeficiency Virus Type 1 Infection: Regulation by Interleukin (IL)–2, IL‐15, and Bcl‐2

Zaunders, John J., Moutouh–de Parseval, Laure, Kitada, Shinichi, Reed, John C., Rought, Steffney, Genini, Davide, Leoni, Lorenzo, Kelleher, Anthony, Cooper, David A., Smith, Don E., Grey, Pat, Estaqui

Journal:

The Journal of Infectious Diseases

Year:

2003

Language:

english

File:

PDF, 287 KB

english, 2003

42

Intercalibration of ecotoxicity testing protocols with Artemia franciscana

Manfra, L., Savorelli, F., Di Lorenzo, B., Libralato, G., Comin, S., Conti, D., Floris, B., Francese, M., Gallo, M.L., Gartner, I., Guida, M., Leoni, T., Marino, G., Martelli, F., Palazzi, D., Prato,

Journal:

Ecological Indicators

Year:

2015

Language:

english

File:

PDF, 736 KB

english, 2015

43

Functional Analysis of PvdS, an Iron Starvation Sigma Factor of Pseudomonas aeruginosa

Leoni, L., Orsi, N., de Lorenzo, V., Visca, P.

Journal:

Journal of Bacteriology

Year:

2000

Language:

english

File:

PDF, 999 KB

english, 2000

44

Entwicklungsgeschichte: Bendamustin gestern, heute, morgen

Werner, Walter, Herold, Michael, Ruffert, Klaus, Merkle, Karlheinz, Brakhage, Axel, Leoni, Lorenzo, Cheson, Bruce D.

Journal:

Year:

2013

Language:

german

File:

PDF, 899 KB

german, 2013

45

Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy

Hustinx, Steven R., Hruban, Ralph H., Leoni, Lorenzo M., Iacobuzio-Donahue, Christine, Cameron, John L., Yeo, Charles J., Brown, Priscilla N., Argani, Pedram, Ashfaq, Raheela, Fukushima, Noriyoshi, Go

Journal:

Cancer Biology & Therapy

Year:

2005

Language:

english

File:

PDF, 686 KB

english, 2005

46

Gαi2 expression, hypertension and insulin resistance

Sartori, Michelangelo, Ceolotto, Giulio, Papparella, Italia, Lenzini, Livia, Leoni, Matteo, Calò, Lorenzo A, Semplicini, Andrea

Journal:

Journal of Hypertension

Year:

2006

Language:

english

File:

PDF, 116 KB

english, 2006

47

Concordant Loss of MTAP and p16/CDKN2A Expression in Gastroesophageal Carcinogenesis

Powell, Eric L, Leoni, Lorenzo M, Canto, Marcia I, Forastiere, Arlene A, Iocobuzio-Donahue, Christine A, Wang, Jean S, Maitra, Anirban, Montgomery, Elizabeth

Journal:

American Journal of Surgical Pathology

Year:

2005

Language:

english

File:

PDF, 1.39 MB

english, 2005

48

Reduced DNA methylation and hydroxymethylation in patients with systemic mastocytosis

Leoni, Cristina, Montagner, Sara, Deho', Lorenzo, D'Antuono, Rocco, De Matteis, Giovanna, Marzano, Angelo V., Merante, Serena, Orlandi, Ester M., Zanotti, Roberta, Monticelli, Silvia

Journal:

European Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 825 KB

english, 2015

49

Aetiology and outcome of pneumoniae in HIV-positive patients in the antiretroviral era

Leoni, Maria C, Mussa, Marco, Chieffo, Gabriella, Minoli, Lorenzo, Seminari, Elena, Provini, Martino, De Silvestri, Annalisa, Marone, Piero

Journal:

Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 572 KB

english, 2017

50

Bone marrow adipocytes support haematopoietic stem cell survival

Mattiucci, Domenico, Maurizi, Giulia, Izzi, Valerio, Cenci, Lorenzo, Ciarlantini, Marco, Mancini, Stefania, Mensà, Emanuela, Pascarella, Raffaele, Vivarelli, Marco, Olivieri, Attilio, Leoni, Pietro, P

Journal:

Journal of Cellular Physiology

Year:

2017

Language:

english

File:

PDF, 1.39 MB

english, 2017